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The BBOP Study
This research is being conducted to find out if the interaction of genes, environment, and lifestyle early in disease can help predict juvenile idiopathic arthritis (JIA) outcomes such as joint damage and diminished quality of life. In particular we hope to answer the following questions:
  1. Does stress make arthritis worse, especially in those with certain genes?
  2. Does infection make arthritis outcomes worse, especially in those with certain genes?
  3. Does nutrition, physical activity, exposure to tobacco smoke and physical trauma predict  damage to the bone and cartilage in the joints?
With the help of everyone involved in the study we hope to develop ways of better predicting JIA outcomes by looking at a patient’s internal and external environment.
Currently, there are two projects designed to predict outcomes of childhood arthritis. “BBOP” described here, as well as “Research on Arthritis in Canadian Children, emphasizing Outcomes” (REACCH OUT). The two studies are linked. Some children/adolescents who agree to participate in REACCH OUT will also be invited to participate in BBOP.  The BBOP study will be carried out over a 2 year time period and will have 5 visits in total. The REACCH OUT study continues for 3 additional years (with only 1 visit per year).

Click here for a timeline of the BBOP study.

Click here for a summary of research projects investigating childhood arthritis in Canada.
Pediatric Rheumatology Centers participating in the BBOP study


Scientific Meetings, Publications, and BBOP In the media

The BBOP study and other rheumatological studies were discussed at the recent meeting of the Canadian Alliance for Pediatric Rheumatology Investigators that was held in Saskatoon, SK (June 17-20, 2009). Click here for a short article on the meeting. 
As the BBOP research study progresses we hope to have a number of publications and other printed material that may be useful to people interested in the  project.




Useful links

Your gateway to arthritis research and development in Canada

Canadian Alliance for Pediatric Rheumatology Investigators (CAPRI)
Click here for a link to a web resource for parents and children involved in clinical studies.

 Participating Sponsors of the BBOP Study 

Canadian Institutes for Health Research
Institute of Muskuloskeletal Health and Arthritis 
 Institute of Infection and Immunity
The Arthritis Society
The Canadian Arthritis Network
University of Saskatchewan
Manitoba Institute of Child Health
McGill University, Division of Pediatric Rheumatology
Memorial University
University of British Columbia, Division of Pediatric Rheumatology
University of Sherbrooke

















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